Past Research Studies

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COVID-19 Study: PANORAMIC

This study, sponsored by the University of Oxford, is now considered the fastest recruiting trial for COVID-19 with over 26,000 participants taking part from across 65 sites. 

The eligibility criteria for this trial:

• You are currently experiencing COVID-19 symptoms beginning in the last 5 days
• And: You have had a positive PCR or Lateral Flow test for COVID-19
• And: You are aged 50 or over, or aged 18 or over with a listed pre-existing condition

Currently active: Yes, recruitment ongoing until end of March 2024

CHIP

Care of housebound patients in primary care (The CHIP Study)

A survey for clinicians about what impact COVID-19 has had on care delivering to housebound patients (defined here as  people who are unable to attend the GP surgery). 

 These are an under researched group with complex health and social needs. The purpose of the clinician survey is to find out about the workforce involved in home visits, initiatives for housebound and/or frail patients and changes to the care of housebound patients due to the COVID-19 pandemic

Aims:

• To explore clinician views on changes to the delivery of care to housebound patients due to the COVID-19 pandemic
• To assess the feasibility of using a new network of trainees and health professionals in primary care to carry out high quality research

This study has now ended. 

Integrated Bipolar Parenting Intervention

This study has now closed for recruitment. 

CLASP

Cancer: Life Affirming Survivorship support in Primary care

The CLASP study aimed to evaluate an online intervention offering lifestyle and wellbeing support for cancer survivors, called Renewed. The intervention was developed using feedback from patients and healthcare professionals and provides modules for lifestyle (healthy eating, weight management, physical activity) and well-being (coping with emotional distress, reducing fatigue). The primary objective was to investigate whether the web-based Renewed programme resulted in a difference in quality of life at 6-month follow-up compared to treatment as usual. We are still awaiting the findings of this study.

This study has now ended. 

Convalescent Serology

This study, led by Public Health England and the University of Oxford, is looking at blood samples from patients who have recovered from COVID-19. Blood samples taken from patients who have had and are recovering from a confirmed COVID-19 infection help researchers to understand the antibody response following infection. This in turn will help to develop new tests for detecting the coronavirus infection. Blood samples are taken at the following dates post infection: 3-6 weeks, 12 weeks, 20 weeks, 9 months and 12 months.

This study has now ended. 

IsoFit-BP

Isometric exercise for people with raised Blood Pressure

Support a local piece of research developed through the University of Kent, Canterbury Christ Church University and East Kent Hospitals University Foundation Trust, IsoFIT-BP!

Within the UK approximately 8 million people are affected by high blood pressure (BP). Standard treatment normally includes changes in lifestyle and/or medication, however, more than half of patients fail to control their BP due to unpleasant side effects associated with medication, and the difficulty of complying with exercise recommendations (at least 150 minutes a week of moderate intensity activity) and dietary changes. The aim of IsoFIT-BP is to find out whether a particular form of static exercise - isometric exercise - is efficient in reducing BP in those with mild hypertension and subsequently whether nurses and allied health professionals can deliver these exercises in a primary care NHS setting.

This study has now ended. 

Low Mood and Anxiety Clinic

Newton Place Surgery previously worked in partnership with P1vital Products Ltd, Canterbury Coastal CCG, the University of Kent and Mind on a research project funded by Innovate UK to provide a walk in clinic to patients registered with a Faversham GP practice for depression and anxiety. The project involved implementing a new service incorporating digital technology (i-spero®) within a multi-disciplinary team of healthcare professionals with specialist training.

This study has now ended. 

RECAP

Remote COVID-19 Assessment in Primary Care

The RECAP project was a collaborative effort between the University of Oxford and Imperial College London, that aimed to develop a tool to assist primary care providers in the identification of COVID-19 patients who may be at risk of becoming severe. It also aimed to facilitate the early escalation of treatment in order to improve patient outcomes. The study found that both RECAP models were valid tools to assess COVID-19 patients in the community.

Newton Place successfully recruited 13 patients to take part in the trial.

REDUCE

ReviEwing long term anti-Depressant Use by Careful monitoring in Everyday practice

Newton Place Surgery are working alongside the University of Southampton to identify feasible, safe, reliable and cost-effective ways of helping patients withdraw from long-term antidepressant use, where appropriate. The researchers are looking to explore the difficulties people experience when withdrawing and identify factors that patients and practitioners think might help people to withdraw.

This study has now ended. 

Relieve IBS-D

Double-blinded randomised placebo controlled trial of Enterosgel (polymethylsiloxane polyhydrate) for the treatment of IBS with diarrhoea (IBS-D)

This study looked at the treatment of Irritable Bowel Syndrome with diarrhoea (IBS-D). The primary objective was to test the effectiveness of a treatment called Enterosgel compared with a placebo in terms of patient reported outcomes for stool consistency and abdominal pain. Enterosgel was shown to improve stool consistency, abdominal pain, stool frequency and urgency and is now considered safe and effective in IBS-D, providing an alternative to the limited current treatment option.

This study has now ended. 

Retrospective Survey of Prevention, Treatment, Occurrence and Outcomes of Covid-19 in the community

Newton Place Surgery asked patients to complete a survey run by the University of Southampton to help researchers understand how to beat Coronavirus. This online survey aims to inform the management of the Covid-19 pandemic by describing use of preventive behaviours, transmission to household contacts, occurrence of infections, the clinical features, use of treatments, and outcomes of people who have experienced suspected COVID-19 illness or any respiratory tract infection during the global pandemic, whether confirmed COVID-19 or not, and the preventive behaviours and treatments of those who have not experienced a suspected COVID-19 illness.

This study has now ended. 

Psychological Impact of Covid-19

To help increase our knowledge of how coronavirus and the changing restrictions have impacted mental health, patients were asked to complete a short, 15 minute questionnaire on how they are coping during the pandemic. The responses are being used to support our understanding of how mental health and wellbeing has been affected by the pandemic and also what may be helpful for people during this time. Newton Place was overwhelmed with the response rate for this research project and would like to thank all patients who took the time to participate.

This study has now ended. 

The PRINCIPLE Trial

PRINCIPLE is another clinical trial led by the University of Oxford exploring treatments for COVID-19. So far over 11,000 patients have taken part in this study from practices across England. The eligibility criteria are as below:

• You are currently experiencing COVID-19 symptoms for 14 days or less
• AND: You have had a positive test for COVID-19 in the last 14 days
• AND: You are aged 18 or over

This study has now ended

SAFER

Screening for Atrial Fibrillation with ECG to Reduce stroke

Atrial fibrillation (AF) is a common irregular heartbeat, and is a major risk factor for stroke unless treated with medication.

We (researchers at the University of Cambridge and the University of Oxford) want to find out whether a national screening programme for atrial fibrillation (i) is possible/achievable, (ii) will prevent strokes and (iii) is good value for money for the NHS.

We are inviting patients aged 70 years and over to take part in a research trial that aims to answer these questions. If you have atrial fibrillation you may still be able to take part.

If you agree to take part, we will ask for your consent to give us access to relevant information from your medical and other health-related records. This will be information related to stroke and associated conditions (you can read more about this later in this information sheet). We will make sure that this information is looked after securely, remains confidential and is only used for the purposes described – all in accordance with the General Data Protection Regulation.

You may or may not be offered screening for atrial fibrillation as part of the trial. If you are offered atrial fibrillation screening we will send you further information about this and you can choose then whether you would like to be screened or not.

This study has now ended

HipDyS

Evaluation of aid to diagnosis of congenital dysplasia of the hip in general practice: controlled randomised trial.

When you come for baby's 6-8 week check, the GP will examine your baby's hips. A research trial is being conducted which seeks to improve the way the 6-8 week checks are carried out. The research team will follow your child's care through the NHS for 2 years. This is needed to find out if your child has always had normal hips, or if the child has ever been to hospital for a hip problem. Also, as part of the research, the surgery staff may send you questionnaires to ask you about your appointment. 

You can opt out of this research study. Opting out means the doctor will continue the examination as routine care and no date will be collected by the research team. You will also not be contacted to complete the questionnaires. 

This study has now ended.