Current Studies

 

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FEATURED COVID-19 STUDY: PANORAMIC

Platform Adaptive trial of NOvel antiviRals for eArly treatMent of COVID-19 In the Community

PANORAMIC is a UK national priority clinical trial seeking new antiviral treatments for COVID-19 in the community. This study, sponsored by the University of Oxford, is now considered the fastest recruiting trial for COVID-19 with over 25,000 participants taking part from across 65 sites. PANORAMIC is one of Newton Place most recent studies, but in the few months we have been open to recruitment it has been extremely successful. The eligibility criteria for this trial are below:

  • You are currently experiencing COVID-19 symptoms beginning in the last 5 days.
  • AND: You have had a positive PCR or Lateral Flow test for COVID-19
  • AND: You are aged 50 or over, or aged 18 or over with a listed pre-existing condition.

If you fit the above description and wish to take part in this study, please click here for more information or contact the Newton Place Research Team

Currently active: Yes, 46 patients from Newton Place have taken part in this study. 

 

Dementia Research

The number of people with dementia is set to double over the next 30 years, making the condition one of the biggest challenges we face today.

Unfortunately, our knowledge of dementia currently lags behind that of other major conditions, such as cancer or heart disease. It is only through research that we can understand what causes the disease, develop effective treatments, improve care and hopefully one day find a cure. However, in order for research to progress, we need more people to take part in more studies.

This is why the National Institute for Health Research (NIHR) in partnership with Alzheimer Scotland, Alzheimer's Research UK and Alzheimer's Society have developed Join Dementia Research, a service that allows people to register their interest in participating in dementia research.

When you sign up, the information you provide is used to match you to studies you may be able to take part in, both online, nationally and in your local area. The service is able to connect registered volunteers with dementia researchers across the UK who are searching for participants to join their studies.

Join Dementia Research delivers new opportunities for people to play their part in beating dementia. By participating, you can make a real difference to the future of dementia care, diagnosis and treatment. For more information, or to sign up, please follow this link

 

The PRINCIPLE Trial

Another clinical trial led by the University of Oxford exploring treatments for COVID-19 is called PRINCIPLE. Ten patients from Newton Place have already taken part in this study, along with over 4,500 people from across England. The eligibility criteria are as below:

  • You are currently experiencing COVID-19 symptoms for 14 days or less.
  • AND: You have had a positive test for COVID-19 in the last 14 days.
  • AND: You are aged 18 or over.

If you fit the above description and wish to take part in this study, please click here for more information or contact the Newton Place Research Team.

Currently active: Yes, recruitment has begun.

 

Convalescent Serology

This study, led by Public Health England and the University of Oxford, is looking at blood samples from patients who have recovered from COVID-19. Blood samples taken from patients who have had and are recovering from a confirmed COVID-19 infection help researchers to understand the antibody response following infection. This in turn will help to develop new tests for detecting the coronavirus infection. Blood samples are taken at the following dates post infection: 3-6 weeks, 12 weeks, 20 weeks, 9 months and 12 months.

Currently active: Yes, 22 patients from Newton Place are already taking part in this study. 

 

REDUCE

Reviewing long term anti-Depressant Use by Careful monitoring in Everyday practice

Newton Place Surgery are working alongside the University of Southampton to identify feasible, safe, reliable and cost-effective ways of helping patients withdraw from long-term antidepressant use, where appropriate. The researchers are looking to explore the difficulties people experience when withdrawing and identify factors that patients and practitioners think might help people to withdraw.

Please contact the Newton Place Research Team for more information or if you would be interested in taking part.

Currently active: Yes, recuitment has begun. 

 

MAGNIFY

Maximizing Adherence and Gaining New Information For Your COPD

Previous research has shown that poor treatment adherence in patients with chronic obstructive pulmonary disease (COPD) is associated with poor clinical outcomes, such as worsening symptoms. Newton Place Surgery is participating in a research study called MAGNIFY which aims to support treatment adherence in those with COPD through the use of a new type of device. This technology monitors inhalations and sends messages to the user’s smartphone to remind them to take their daily dose. It also allows healthcare professionals to monitor patients’ inhaler use and provide more personalised support. MAGNIFY is managed by the Observational and Pragmatic Research Institute (OPRI) and funded by Novartis AG. It is already being conducted at approximately 200 GP practices across the UK.

If you have a current diagnosis of COPD and would like to find out more about MAGNIFY, please contact the Newton Place Research Team.

Currently active: Yes, 4 patients from Newton Place are taking part.

 

IsoFit-BP

Isometric exercise for people with raised Blood Pressure

Support a local piece of research developed through the University of Kent, Canterbury Christ Church University and East Kent Hospitals University Foundation Trust, IsoFIT-BP!

Within the UK approximately 8 million people are affected by high blood pressure (BP). Standard treatment normally includes changes in lifestyle and/or medication, however, more than half of patients fail to control their BP due to unpleasant side effects associated with medication, and the difficulty of complying with exercise recommendations (at least 150 minutes a week of moderate intensity activity) and dietary changes. The aim of IsoFIT-BP is to find out whether a particular form of static exercise - isometric exercise - is efficient in reducing BP in those with mild hypertension and subsequently whether nurses and allied health professionals can deliver these exercises in a primary care NHS setting.

If you are interested in finding out more or taking part in this study, please contact the Newton Place Research Team. You can also visit the study website: IsoFIT-BP Study

Currently active: Yes, recuitment has begun.

 

ATTACK

Aspirin To Target Arterial events in Chronic Kidney disease
Does low-dose aspirin reduce the chance of a heart attack or stroke in patients with chronic kidney disease (CKD)? This is a large-scale academic study led by the University of Southampton, to see whether or not patients with chronic kidney disease should be taking aspirin daily to prevent a first heart attack or stroke. It is recruiting patients from GP practices across the UK, and looks to invite 198,000 patients.

Currently active: Yes, recruitment has begun.

 

STREAM

Screen and treat for Malnutrition

The University of Southampton has developed an intervention to help doctors and nurses in general practice to check if adults over the age of 75 who live at home are at risk of malnutrition. The STREAM study aims to assess the effectiveness of this intervention. Newton Place are identifying eligible patients over 75 to compare the newly developed intervention with usual care in order to see what effect it has on participants’ quality of life and infections over 18 months.

Currently active: Yes, recuitment has begun. 

 

APPLE-Tree

Active Prevention in People at risk of dementia through Lifestyle, behaviour change and Technology to build Resilience

APPLE-Tree is a study led by the research team at the University College London intending to develop and test a prevention programme to reduce the risk of developing dementia in people over the age of 60. Their main aims are: 

  • To assess whether the APPLE-Tree intervention is acceptable and feasible to deliver in practice.
  • To confirm if the APPLE-Tree intervention reduces cognitive decline over two years.
  • To explore what factors may determine decisions of NHS and third sector organisations not taking part in the trial, regarding whether or not they decide to adopt the new intervention, if it is demonstrated to be clinically effective and cost-effective.

If you are interested to find out more about APPLE-Tree please contact the Newton Place Research Team.

Currently active: Yes, recuitment has begun.

 

Immune Defence

The Immune Defence Study is part of the RECUR Programme that is run by the University of Southampton. This study is designed to determine if using nasal sprays, being more physically active and reducing stress, can help people reduce the frequency and severity of respiratory infections (such as colds, sore throats, sinus, chest or ear infections, flu and COVID-19). Immune Defence is aiming to involve approximately 200 GP practices and up to 15000 patients who may be at risk from respiratory infections.

Currently active: Yes, recuitment has begun.